Gene name:
Tnfrsf18 (Gitr) ;
Protein name:
Tumor necrosis factor receptor superfamily member 18 ;
Alternative:
Glucocorticoid-induced TNFR-related protein ;
CD:
CD357 ;
Organism:
Mouse (Mus musculus).
General Annotation
Sub Unit:
Binds to TRAF1, TRAF2, and TRAF3, but not TRAF5 and TRAF6 (By similarity). Binds through its C-terminus to SIVA1/SIVA.
Function:
Receptor for TNFSF18. Seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. Mediated NF-kappa-B activation via the TRAF2/NIK pathway.
Subcellular Location:
Isoform D
Secreted
Protein Attributes:
50:
MGAWAMLYGV | SMLCVLDLGQ | PSVVEEPGCG | PGKVQNGSGN | NTRCCSLYAP |
100:
GKEDCPKERC | ICVTPEYHCG | DPQCKICKHY | PCQPGQRVES | QGDIVFGFRC |
150:
VACAMGTFSA | GRDGHCRLWT | NCSQFGFLTM | FPGNKTHNAV | CIPEPLPTEQ |
200:
YGHLTVIFLV | MAACIFFLTT | VQLGLHIWQL | RRQHMCPRET | QPFAEVQLSA |
228:
EDACSFQFPE | EERGEQTEEK | CHLGGRWP
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Mouse
Human
ELISA Kit for Mouse Tumor necrosis factor receptor superfamily member 18
ELISA Kit for Mouse Tumor necrosis factor receptor superfamily member 18
CLIA Kit for Mouse Tumor necrosis factor receptor superfamily member 18
CLIA Kit for Mouse Tumor necrosis factor receptor superfamily member 18
Polyclonal Antibody for Mouse Tumor necrosis factor receptor superfamily member 18
Polyclonal Antibody for Mouse Tumor necrosis factor receptor superfamily member 18
Monoclonal Antibody for Mouse Tumor necrosis factor receptor superfamily member 18
Monoclonal Antibody for Mouse Tumor necrosis factor receptor superfamily member 18
Protein for Mouse Tumor necrosis factor receptor superfamily member 18
Protein for Mouse Tumor necrosis factor receptor superfamily member 18
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM A)
strain :
C3H .
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE (ISOFORM A)
strain :
BALB/c .
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS B; C AND D)
tissue :
Thymus .
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM A)
strain :
C57BL/6J .
tissue :
Thymus .
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INTERACTION WITH SIVA1;MUTAGENESIS OF SER-199; GLU-201; CYS-204; PRO-209 AND 210-GLU--GLU-212